By Judith Hibbard MD

This factor Obstetrics and Gynecology Clinics examines clinical problems in being pregnant. visitor Editor Dr. Judith Hibbard has assembled a panel of specialists who provide experiences on subject matters together with Preeclampsia, Peripartum cardiomyopathy, Pregestational diabetes, bronchial asthma administration, administration of renal affliction, Renal transplant recipients and being pregnant, Sickle disorder and being pregnant, Thyroid ailment, Gestational diabetes, being pregnant after gastric skip, Thromboprophylaxis in being pregnant, Cholestasis of being pregnant, and moral concerns in obstetrics.

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Additional info for Update on Medical Disorders in Pregnancy, An Issue of Obstetrics and Gynecology Clinics (The Clinics: Internal Medicine)

Sample text

22. Schatz M, Dombrowski MP, Wise R, et al. The relationship of asthma medication use to perinatal outcomes. J Allergy Clin Immunol 2004;113(6):1040–5. 23. Suissa S, Ernst P, Benayoun S, et al. Low-dose inhaled corticosteroids and the prevention of death from asthma. N Engl J Med 2000;343(5):332–6. 24. Cockcroft DW, Murdock KY. Comparative effects of inhaled salbutamol, sodium cromoglycate, and beclomethasone dipropionate on allergen-induced early asthmatic responses, late asthmatic responses, and increased bronchial responsiveness to histamine.

Two recent, large, multicenter, prospective cohort studies evaluated Asthma in Pregnancy the effects of asthma on perinatal outcomes. First, Bracken and colleagues4 prospectively followed 2205 pregnancies and showed that preterm delivery was not associated with asthma; however, requirement of theophylline or oral corticosteroids was associated with a statistically significant reduction in gestational age at delivery. Small-for-gestational-age infants and preeclampsia were associated with moderate asthma or those with daily symptoms.

The course of asthma during pregnancy, post partum, and with successive pregnancies: a prospective analysis. J Allergy Clin Immunol 1988;81(3):509–17. 17. National Asthma Education and Prevention Program expert panel report. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. J Allergy Clin Immunol 2005;115(1):34–46. nhlbi. pdf. Accessed January 21, 2010. 18. Schatz M, Dombrowski MP, Wise R, et al. Spirometry is related to perinatal outcomes in pregnant women with asthma.

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