By E Y Adashi; P C K Leung

This authoritative and modern reference presents the main updated medical and theoretical info on hand on ovarian body structure. greater than seventy five of the world's prime specialists in pertinent scientific and learn parts study all stages of the ovarian lifestyles cycle, synthesizing molecular and mobile element with classical body structure and pathophysiology in a hugely equipped demeanour. insurance starts off with a close description of the follicular equipment and its legislation, after which strikes directly to oocyte maturation, ovulation, and corpus luteum formation. unique emphasis is put on cyclic ovarian mobilephone loss of life, a facet of ovarian body structure now coming to the fore. shut consciousness can also be given to intraovarian rules via progress elements, cytokines, hormones, and regulatory peptides. a bit on pathophysiology contains a well timed dialogue on ovulation induction and gonadotropin remedy

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And Hsueh, A. J. W. (1981). Stimulation of b2adrenergic responsiveness by follicle-stimulating hormone in rat granulosa cells in vitro and in vivo. Endocrinology 108, 2170–2178. Aguado, L. , Petrovic, S. , and Ojeda, S. R. (1982). Ovarian b2-adrenergic receptors during the onset of puberty: Characterization, distribution, and coupling to steroidogenic responses. Endocrinology 110, 1124–1132. Flerko, B. (1977). Sympathetic nerve function in the ovary. In Endocrinology, Vol. 1: Proceedings of the V International Congress of Endocrinology, ed.

However, although KL and c-kit have been detected in primate nongrowing follicles [25, 26], bFGF was not detected in human follicles before the preantral stage [27]. In cynomolgus monkeys, transforming growth 30 PART I • The Ovarian Follicular Apparatus: Operational Characteristics factor-alpha (TGF-a) is absent in GC from resting follicles and is present in GC from growing follicles [25]. Because TGF-a stimulate GC proliferation [28], it could be tempting to speculate that TGF-a may play a role in the initiation of follicular growth via induction of GC proliferation.

05 vs control for that time period (n = 6 for all groups). (From Ref. ) the peripheral nervous system results in rapid activation of NGF synthesis and NGF-dependent processes (see [145]). The ovary behaves similarly, as shown by the dramatic increase in ovarian trkA gene expression and the simultaneous elevation in NGF mRNA levels that accompanies and follows the first preovulatory surge of gonadotropins [103]. The increase in trkA mRNA content is striking (> 100-fold); it lasts for at least 8 hours, is mainly observed in cells of the follicular wall and interstitial gland, and is accompanied by a corresponding increase in immunoreactive trkA protein.

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