By Carl C Lindegren

THE chilly conflict IN BIOLOGY. through Carl C. Lindegren. Ann Arbor, MIich.,
Planarian Press, Inc., 1967. 133 pp. $6.50.
This problem to a few of the adored dogmas of genetics and evolution
is attention-grabbing examining. Lindegren's reviews in regards to the suppression of
views which problem the underlying assumptions of medical research
are rather poignant in view of his hassle in getting this e-book published,
even even though he's a great geneticist.
The first bankruptcy, "The online game of Science," and the ultimate 4 chapters,
concerning the phone thought, the foundation of lifestyles, organic evolution, and the
living kingdom, are proper to the suggestions of any biologist. Many scientists
will be aggravated by way of Lindegren's research, yet by no means bored, and plenty of will
perhaps notice how good taken Lindegren's criticisms usually are.
Anyone who has the growth of the Lysenko-Michurin stranglehold
upon Russian genetics, which has been lately comfy, will locate a
lucid dialogue of a few of the experiments of this college. Interspersed in
this portion of the ebook are extra reflections upon the influence of enforced
dogma upon clinical development. Geneticists will enjoy the personal
biographies integrated in "The Architects of Morganism-Mendelism," and
should take to center Lindegren's reviews pertaining to cytoplasmic inheritance
and the ongoing problems in defining the gene.
It is impossible that any scientist who has been knowledgeable lately in
this nation can learn this booklet with out changing into indignant at least one time or
twice. time and again, substitute motives of the information pointed out ensue to the
reader. i'm confident, even if, that Lindegren's iconoclasm, good founded
in the clinical strategy, will greater than pay off the reader of this book.

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A gene mutation or point mutant in s uch experiments means, of course, a mutant which with the best available methods does not show a cytological rearrangement. But not all mutants can be checked cytologically. In the salivary chromosomes some regions are more favorable than others . In favorable regions a deficiency , down to a s ingle band, can be checked easily ; in others it is more difficult. Small inversions are even more difficult. Inversions of a few bands may or may not be detected without a very detailed study , wh ich usually cannot be made in connection with large - scale quantitative work.

9. A diagrammatic representation of a chiasma as described by Janssens. The Genes are Arranged in Linear Order on the Chromosomes (Sturtevant , 1913) In 1913, A. H. Sturtevant showed that genetical analysis of DrosojJhila hybrids could show not only that crossing-over occurred but that the invisible genes are arranged on the chromosome in a linear array corresponding to the linear order of the visible "beads" seen by the cytologist. Sturtevant arrived at his theory of the linear order of the genes by studying the progeny of a female which was hybrid for three different defects.

E. , were considered important; the same catholicity prevailed generally in the third generation. The present fourth generation has been overwhelmed by the mass of precisely-detailed and revolutionary discoveries of biochemistry, and has been completely unable to consider the biological problem in its broadest aspects hence, an operational, almost purely pragmatic, point of view prevails among the current geneticists. " Morgan, Bateson, Belling and Darlington continued 32 COLD WAR IN BIOLOGY in Mendel's foot steps with the concept of a discrete particulate gene, but this view has been rejected This chapter will attempt to present the views of the different theorists and the steady evolution from a conceptual to an operational attitude toward the gene .

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