By F. W. Spiers

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Extra info for Radioisotopes in the Human Body. Physical and Biological Aspects

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S. G o v t . Printing Office, Washington, D . C . (1961). 11. D . Strominger, J. M . Hollander, and G. T . Seaborg, Rev. Mod. , 3 0 : 585 (1958). 12. H . A Bethe, Hdbk. Physik, 2 4 ( 1 ) : 273 (1933). 13. N . Bohr, Kgl. Danske Videnskab. Selskab, Mat. Fys. , 18: N o . 8 (1948). 14. E. Fermi, Phys. , 5 7 : 485 (1940). 15. O. Halpern and H . Hall, Phys. , 7 3 : 477 (1948). 16. L. H . Gray, / . Chem. , 4 8 : 172 (1951). 17. D . E. , Cambridge University Press, Cambridge, England, 1955, Chap. 1. 18.

TWO-COMPARTMENT MODEL WITHOUT BACK-TRANSFERENCE Consider two compartments in which an isotope is transferred at a rate K from compartment 1 to compartment 2, from which there is further transference of the isotope at a rate K ; this second transference is assumed to be out of the system without any back-transference to the first compartment, as in Fig. 5b. If the physical decay constant is A, the activity at any time t in compartment 1 will be given by Eq. 10) + KJt] where Q is the initial activity acquired by compartment 1.

Data from the Report of Committee II of ICRP ( 1 9 5 9 ) on "Permissible Dose for Internal Radiation" will be drawn on for parts of this chapter, but it should be pointed out that the ICRP data are at present being considerably revised and extended. The existing data, however, adequately illustrate the principles under discussion. 1 1. 1. CHEMICAL COMPOSITION OF THE BODY Extensive data on the average chemical composition of the body and its principal organs are given in the Report of Committee II of I C R P and only limited information will be included here.

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