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Additional info for Radiofrequency Ablation for Cancer Current Indications, Techniques and Outcomes
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Modeling of the thermal gradient about a monopolar RF electrode. In these simulations, RF power was titrated to a maximum tissue temperature of 95°C for 6 minutes. Temperature is highest superiorly, and drops interiorly. 8 cm in diameter. 7-cm diameter achieved in the presence of normal blood flow (10 mg/100 mL/min). 18 M. N. Goldberg for coagulation. Several studies exploring altered tissue perfusion to increase the ablative zone through either mechanical occlusion or pharmacologic agents strongly support the contention that perfusion-mediated tissue cooling is responsible for this reduction in observed coagulation.