By Fiona Campbell, Caroline S. Verbeke (auth.)

Pathology of the Pancreas: a realistic Approach covers all of the diagnostic entities in grownup pancreatic pathology, supplying wide illustrations and tables to help the pathologist on the time of diagnostic reporting of histological and cytological specimens. power pitfalls and mimics in pancreatic pathology are highlighted and illustrated, and tips is supplied relating to find out how to realize and steer clear of them.

Pathology of the Pancreas: a pragmatic Approach permits the pathologist to acknowledge a few of the pathological entities and supply the main details of their pathology experiences, that's valuable for the person patient’s extra administration. it's in response to the newest diagnostic algorithms, foreign consensus guidance, and structures for affliction type, staging and grading. scientific info is usually integrated, the place it is crucial for the multidisciplinary group administration discussion.

Pathology of the Pancreas: a pragmatic Approach is a bench ebook for daily use beside the microscope and gives the diagnostic pathologist with a finished, well-illustrated and largely cross-referenced method of pancreatic pathology.

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Extra resources for Pathology of the Pancreas: A Practical Approach

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Some of 15 b Note the apparent extension of islet cells in between adjacent acini (a). Immunostaining highlights the presence of numerous PP-cells (b) the extrainsular endocrine cells that are present in large pancreatic ducts may also produce serotonin, implying that these cells may be the origin of the very rare true carcinoid tumors of the pancreas (see Chap. 20). In contrast to the paucity of extrainsular endocrine cells in postnatal life, numerous endocrine cells occur in close contact with the duct epithelium during intrauterine development.

Towards its distal end, the main pancreatic duct changes direction and runs in a nearly axial plane towards the ampulla, with the result that this particular part of the main pancreatic duct may be displayed as a more longitudinal section (see Figs. 6). If the main pancreatic duct is dilated significantly, the distal end of the duct may be represented in a longitudinal fashion in more than one specimen slice. However, if the duct is of a normal caliber and the slices are thicker than 3 mm, this part of the pancreatic duct may remain hidden within a single specimen slice.

29 Junction of ampulla of Vater and common bile duct: at the junction of both structures (arrows), the thin and lacunar muscle coat and the flatly pleated epithelium of the bile duct abruptly change into the deeply furrowed epithelium of the ampulla and the thick sphincter muscle (A ampulla, CBD common bile duct, Pa pancreatic parenchyma, P papilla of Vater) (Image courtesy and copyright of Paul Brown, The Leeds Teaching Hospitals NHS Trust, Leeds, UK) function (Fig. 30). In 80 % of individuals, pancreatic tissue is found in the minor ampulla, which may or may not show a connection with the pancreas proper (see Fig.

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