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Most of the current eﬀorts on nacre mimicking have thus been targeted towards the laminated structures and the alternating hard and soft components. 159–162 Further, silk-mimetic proteins have been fabricated using a variety of processing routes. 168 These methodologies have a high potential to impact a large range of applications, from electronics to biomedicine. Bone and teeth structures, although an inspiration, are not subjects of recent studies on replacement materials for these tissues; most studies for replacement of these hard tissues169 are based on replacement of function rather than structure.
Tsioris, F. G. Omenetto and D. L. Kaplan, Adv. , 2010, 22, 249. 158. I. Agnarsson, A. Dhinojwala, V. Sahni and T. A. Blackledge, J. Exp. , 2009, 212, 1989. 159. J. G. Hardy and T. R. Scheibel, Biochem. Soc. , 2009, 37, 677. 160. J. G. Hardy and T. R. Scheibel, Prog. Polym. , 2010, 35, 1093. 161. H. J. Kim, U. J. Kim, H. S. Kim, C. M. Li, M. Wada, G. G. Leisk and D. L. Kaplan, Bone, 2008, 42, 1226. 162. B. D. Lawrence, J. K. Marchant, M. A. Pindrus, F. G. Omenetto and D. L. Kaplan, Biomaterials, 2009, 30, 1299.