By Hermann Giersberg (auth.)

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Extra info for Hormone

Sample text

In der Schilddrüse wird das Hormon mit einem Eiweißkörper verankert und als Thyreoglobulin im Schilddrüsenkolloid gestapelt. Bei der Absonderung des Hormons ins Blut aber wird das hochmolekulare Thyreoglobulin durch proteolytische (eiweißlösende) Fermente wieder zerlegt und das Thyroxin im Blut locker an Plasmaeiweißstoffe gebunden verfrachtet. Die Bildung des Thyroxins kann durch Hemmstoffe wie die neuerdings sehr bekannt gewordenen und medizinisch gegen überfunktion der Schilddrüse eingesetzten Verbindungen Thiocyanat und Thiouracil u.

Nun sind freilich die Wirkungen von Zirbel und Thymus nicht so auffällig wie der bisher besprochenen innersekretorischen Organe oder der Keimdrüse oder der 4 Giersberg, Hormone 49 Hypophyse, und man kann sogar daran zweifeln, ob diese bei den Organe überhaupt unter die Drüsen mit innersekretorischer Wirkung eingereiht werden können. VIII. Zirbel und Thymus Zirbel oder Epiphyse Wenn man vorsichtig ist, muß man wohl sagen: mit Recht, denn ein wirklich genauer Nachweis scheint für ihre innersekretorische Wirkung nicht vorzuliegen.

Sind die Ausfälle noch geringer, dann kann noch eine Neigung zu Krampfanfällen zurückbleiben, die besonders dann in Erscheinung tritt, wenn durch Erschöpfung, Fieber oder Schwangerschaft erhöhte 'Anforderungen an den Körper gestellt werden. Solche Neigung zu Krampfanfällen kommt ziemlich häufig bei Kindern im ersten Lebensjahre vor, oft in Verbindung mit Rachitis, um sich dann meist im späteren Leben zu verlieren. Wodurch erklären sich diese Erscheinungen? Bei Ausfall des Epithelkörperchenhormons (= Parathormon) sinkt zunächst die Ausscheidung des Phosphats im Harn; dadurch kommt es zu einer Zunahme des Blutphosphats und als Folge hiervon zu einer Abnahme des Blutkalks.

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