By Siegfried Kasper, Robert Hirschfeld

Knowledgeable precis of our present realizing of bipolar illness, this reference examines current theories, remedy regimens, and clinically correct purposes through international experts in psychiatric learn. Divided into 4 major sections, this consultant delves into the analysis and epidemiology of bipolar ailment and progresses to discussions of sufferer care, rising administration techniques, and the underlying biology of the disorder.

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Extra resources for Handbook of Bipolar Disorder: Diagnosis and Therapeutic Approaches (Medical Psychiatry)

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Berlin: Springer, 1966. 35. Perris C. A study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses. Acta Psychiatr Scand 1966; 42 (suppl 194):172–188. 36. Perris C. The distinction between bipolar and unipolar affective disorders. In: Paykel ES, ed. Handbook of Affective Disorders. Edinburgh: Churchill Livingstone, 1982:43–58. 37. Winokur G, Clayton P, Reich T. Manic Depressive Illness. V. Mosby, 1969. 38. Bertelsen A, Harvard B, Hauge M. A Danish twin study of manic-depressive disorders.

PSYCHOSOCIAL STRESSORS AND SOCIAL SUPPORT Social stressors and low-level social support have been well recognized as risk factors for unipolar and bipolar disorders (42,63,71). However, different kinds of stressors (childhood vs. adulthood life events, acute vs. chronic stressors, positive vs. negative life events) can play different roles in the predisposition for, and precipitation of, different affective episodes. In patients with unipolar major depression and bipolar disorders, the association of acute stressors and the onset of the illness episode become progressively weaker with the increasing number of previous episodes (42,63).

J Clin Psychiatry 1998; 58(12):538–546. Diagnosis of Bipolar Disorder 19 24. Winokur G, Wesner R. From unipolar depression to bipolar illness: 29 who changed. Acta Psychiatr Scand 1987; 76(1):59–63. 25. Mitchell PB, Wilhelm K, Parker G, Austin MP, Rutgers P, Malhi GS. The clinical features of bipolar depression: a comparison with matched major depressive disorder patients. J Clin Psychiatry 2002; 63(1):77–78. 26. Kadrmas A, Winokur G, Crowe R. Postpartum mania. Br J Psychiatry 1979; 135: 551–554.

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