By Linda C. Giudice MD, Johannes L. H. Evers MD, David L. Healy

Written by means of an the world over famous editor workforce, Endometriosis: technology and perform is a cutting-edge consultant to this unusually universal sickness. whereas no reason for endometriosis has been decided, details of contemporary advancements are defined during this textual content, providing perception to enhance administration of indicators medically or surgically. the 1st of its variety, this significant textbook integrates clinical and scientific knowing of this painful sickness supporting to supply greater sufferer care.

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Additional resources for Endometriosis: Science and Practice

Example text

In a few cases ovulation has occurred in the cyst and both cavities were linked. In such cases the endometrial tissue colonized the luteal cyst, showing that, under such circumstances, endometriosis can invade the ovary. They distinguished two types of endometriotic cysts: the red type which is lined by a surface epithelium and a thin layer of highly vascularized stroma without glands covering partially or completely the whitish or slightly pigmented wall, and the black type where the wall is lined by dark, pigmented and fibrotic tissue with scanty vascularization.

The structure demonstrated that the relation to the surface is primary and not secondary, such as would have been implied by Sampson’s [11] original title of “perforating hemorrhagic cysts of the ovary” and by Halban’s lymphatic theory [48]. Hughesdon also discussed the few cases with so-called “deep” ovarian endometriosis and demonstrated on serial sections that although deep, non-cystic lesions are, in a gross sense, in the ovary, the associated layering shows that they have originated at the surface.

However, close scrutiny of some of the original manuscripts from this period has shown that the descriptions evidenced signs of inflammation such as pus, uterine wounds or erosions that were linked to manipulation, an abortion or a syphilitic lesion. The symptoms described were those of an infection and included pain, insomnia, fever, vaginal lesions, dysuria, purulent urine (if the lesion involved the bladder) or purulent stool (if the lesion involved the intestines). There were no descriptions in the Disputatio Inauguralis or in the other later dissertations that could be interpreted as being indicative of endometriosis.

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