By Joseph F. Goldberg, Katherine E. Burdick

A becoming physique of scientific and experimental proof indicates that neurocognitive disorder is a primary but often missed or misidentified element of bipolar affliction. the 1st complete booklet of its sort, Cognitive disorder in Bipolar illness: A advisor for Clinicians compiles the newest facts in neuropsychology, neuroimaging, neurogenetics, and sensible results examine to permit clinicians to extra successfully make the most of pharmacological and psychotherapeutic suggestions of their remedy of bipolar disorder.

This quantity outlines and demystifies present wisdom approximately neuropsychological functioning in bipolar ailment in a reader-friendly, easy-to-understand advisor for practitioners. Its 12 chapters, written by means of 23 internationally-renowned specialist individuals, learn such themes as attentional and govt functioning, neuroimaging and genetic correlates of cognitive functioning, pharmacologic options, bipolar affliction in pediatric sufferers, and cognition around the lifestyles span. The e-book additionally comprises precious bulleted take-home issues on the finish of every bankruptcy that summarize major strategies, in addition to case vignettes and illustrative examples that depict the medical program of particular neurocognitive principles.

utilizing appropriate functions from cognitive neuroscience, Cognitive disorder in Bipolar Disorder offers clinicians with a complete evaluation of brilliant breakthroughs within the evaluate and remedy of sufferers with bipolar sickness. It plows new flooring within the psychological future health undefined, correcting distortions and laying the basis for destiny scientific study during this quickly increasing box

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Extra resources for Cognitive Dysfunction in Bipolar Disorder: A Guide for Clinicians

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1990). Several neuropsychiatric disorders and symptoms have been suggested to relate to specific frontal-striatal loops (Mega and Cummings 1994). The “affective loop” linking the orbitofrontal cortex and anterior cingulate cortex with the ventral striatum is implicated in mood disorders (as illustrated schematically in Chapter 1 of this volume, “Overview and Introduction: Dimensions of Cognition and Measures of Cognitive Function,” Figure 1–1). Structural brain abnormalities in the PFC have been confirmed in patients with bipolar disorder.

The “affective loop” linking the orbitofrontal cortex and anterior cingulate cortex with the ventral striatum is implicated in mood disorders (as illustrated schematically in Chapter 1 of this volume, “Overview and Introduction: Dimensions of Cognition and Measures of Cognitive Function,” Figure 1–1). Structural brain abnormalities in the PFC have been confirmed in patients with bipolar disorder. Histological examination of postmortem tissue has confirmed neuropathology in the anterior cingulate cortex and dorsolateral prefrontal cortex.

Schizophr Res 23:197–204, 1997 Altshuler LL, Ventura J, van Gorp WG, et al: Neurocognitive function in clinically stable men with bipolar I disorder or schizophrenia and normal control subjects. Biol Psychiatry 56:560–569, 2004 Atre-Vaidya N, Taylor MA, Seidenberg M, et al: Cognitive deficits, psychopathology, and psychosocial functioning in bipolar mood disorder. Neuropsychiatry Neuropsychol Behav Neurol 11:120–126, 1998 Basso MR, Lowery N, Neel J, et al: Neuropsychological impairment among manic, depressed, and mixed-episode inpatients with bipolar disorder.

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