By G. Justus Hofmeyr, James P. Neilson, Zarko Alfirevic, Caroline A. Crowther, Lelia Duley, Metin Gulmezoglu, Gillian M. L. Gyte, Ellen D. Hodnett

Pregnancy and Childbirth offers the simplest proof for the care of pregnant ladies to medical professionals, midwives, scholars and parents.  The logical series of chapters and the index supply easy accessibility to the abstracts of over 400 Cochrane systematic reviews.  The e-book serves either as a stand-alone reference, and as a significant other to finding complete reports at the Cochrane Library.

The Cochrane Library is released through John Wiley on behalf of The Cochrane Collaboration.

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Extra info for A Cochrane Pocketbook: Pregnancy and Childbirth (Wiley Cochrane)

Sample text

Search date: December 2005. MAIN RESULTS : Nine trials (15 378 women) are included. 71). However, these differences lost statistical significance when multiple-micronutrient supplementation was compared with iron folic acid supplementation alone. No statistically significant differences were 32 PREGNANCY AND CHILDBIRTH shown for the outcomes of preterm births and perinatal mortality in any of the comparisons. A number of prespecified clinically important outcomes could not be assessed due to insufficient or non-available data from the included trials.

Search date: June 2001. MAIN RESULTS : Seven trials involving 2689 women were included. Six of these trials randomly allocated women to either an oral magnesium supplement or a control group, whilst the largest trial with 985 women had a cluster design where randomisation was according to study centre. The analysis was conducted with and without the cluster trial. 93) compared with placebo. 90) than placebo treated women. In the analysis excluding the cluster randomised trial, the effects of magnesium treatment on the frequencies of preterm birth, low birth weight and small for gestational age were not different from placebo.

17; 11 studies of 4941 women). No significant differences were seen between the zinc and no zinc groups for any of the other primary maternal or neonatal outcomes, except for a small effect favouring zinc for caesarean section (four trials with high heterogeneity) and for induction of labour in a single trial. No differing patterns were evident in the subgroups of women with low versus normal zinc and nutrition levels or in women who complied with their treatment versus those who did not. AUTHORS’ CONCLUSIONS : The 14% relative reduction in preterm birth for zinc compared with placebo was primarily in the group of studies involving women of low income and this has some relevance in areas of high perinatal mortality.

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